From 1961 to 1963 he was senior editor of the script department of the film studio "Belarusfilm", then again "Polymya": literary worker of the department of criticism, editor of the department of science and art. Since 1971 ─ head of the laboratory for teaching literacy, and then the department of scientific literature of the Institute of Pedagogy of the Ministry of Education of the BSSR. In 1981-1983 1986-1990 ─ head of the editorial office of the publishing house "Unatstva", in 1986-1990. - Head of the department of criticism of the magazine "Polymya". Anatoliy Klyshko was the author of "Primer" (1969, 23 editions) and other textbooks and manuals, children's books. The books have been translated into English, German, French.